Category Archives: ANTI-THROMBOTIC DRUGS

CLOPIDOGREL+ASPIRIN (ECOSPRIN PLUS) 75mg/75mg Film-coated Tablet

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ECOSPRIN PLUS 75mg/75mg Film-coated Tablet; box of 30’s

Generic Name:              Clopidogrel+Aspirin
Registration Status:   Registered
Drug Type:                       ANTOTHROMBOTIC DRUG
Principal:                         THE ACME LABORATORIES LTD.


Description:
Clopidogrel bisulfate + Aspirin (ECOSPRIN PLUS) is a fixed-dose combination containing Aspirin and Clopidogrel. Aspirin is an antiplatelet agent. It is an acetylsalicylic acid. Aspirin acts by causing irreversible inhibition of the cyclooxygenase enzyme, which leads to decreased formation of Thromboxane A2. Since platelets do not synthesize new enzyme, the action of Aspirin on platelet cyclooxygenase is permanent, lasting for the life of the platelets (7-10 days). Clopidogrel is a thienopyridine derivative that selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor and the subsequent ADP-mediated activation of the GP llb/llla complex, thereby inhibiting platelet aggregation.

Available in Alu/Alu Blister Pack of 10’s; box of 30 film-coated tablets.

CLOPIDOGREL

clopidogrel-clovix-75mg

CLOVIX 75 mg Film-Coated Tablet; box of 30’s

Generic Name:              Clopidogrel
Registration Status:   Registered
Drug Type:                       ANTI-THROMBOTIC DRUGS
Principal:                         THE ACME LABORATORIES LTD.


Description:
CLOVIX is Clopidogrel, indicated for the prevention of atherosclerotic events in patients with history of symptomatic atherosclerotic disease ( ischaemic stroke, myocardial infarction or established peripheral arterial disease).

Available in blister pack of 10’s, box of 30’s.

DALTEPARIN SODIUM

dalteparin-sodium-eurodal

EURODAL 2500 I.U./0.2mL PFS Solution for Inj.; box of 6’s

Generic Name:              Dalteparin sodium
Registration Status:   Registered
Drug Type:                       ANTI-THROMBOTIC DRUGS
Principal:                         THE ACME LABORATORIES LTD.


Description:
EURODAL is Dalteparin sodium, a low molecular mass heparin sodium derived from pig mucosa with an average molecular weight of 5000. Its antithrombotic effect is dependent on its stability to potentiate the inhibition of Factor Xa and thrombin by antithrombin (AT). Dalteparin sodium has relatively higher ability to potentiate Factor Xa inhibition than to prolong plasma clotting time (APTT). Has smaller effect on platelet function and platelet adhesion than heparin, and thus has only a small effect on primary homeostasis. Still some of the antithrombotic properties of Dalteparin sodium are thought to be mediated through the effect on vessel walls of the fibrinolytic system. It is used in the treatment and prophylaxis of venous thromboembolism and to prevent clotting during extracorporeal circulation. It is also used in the management of unstable angina.

Supplied in 2500 I.U./0.2mL and 5000 I.U./0.2mL Solution for Injection in glass syringe (with stacked needle) of 1’s; Box 6’s.