Category Archives: ANTI-SPASMODIC / ANTI-FLATULENT DRUGS

DOMPERIDONE TAB

domperidone-gastromec

GASTROMEC 10 mg Film-Coated Tablet; box of 100’s

Generic Name:              Domperidone
Registration Status:   Registered
Drug Type:                       ANTI-SPASMODIC / ANTI-FLATULENT DRUG
Principal:                         THE ACME LABORATORIES LTD.


Description:
GASTROMEC is Domperidone, a dopamine receptor (D2) antagonist. Domperidone is a selective peripheral dopamine antagonist at the D2 dopamine receptor in the Chemo-receptor Trigger Zone (CTZ) and stomach. Domperidone does not readily enter the central nervous system (the chemoreceptor trigger zone is considered to lie outside the blood brain barrier). Domperidone increases spontaneous gastric activity and antagonizes dopamine inhibition of gastric emptying. Domperidone has been shown to increase lower esophageal sphincter pressure and promotes esophageal and antral peristalsis and also increases pyloric dilatation. Domperidone increases the frequency, amplitude, duration of duodenal contraction and reduces the small bowel transit time. Domperidone has no acetylcholine like effect.

Available in  Alu-clear PVDC Blister pack of 10’s (Box of 100’s).

DOMPERIDONE SUSP.

domperidone-don-a-60ml

DON-A  5mg/ 5mL Suspension; box of 1’s

Generic Name:              Domperidone
Registration Status:   Registered
Drug Type:                       ANTI-SPASMODIC / ANTI-FLATULENT DRUG
Principal:                         THE ACME LABORATORIES LTD.


Description:
DON-A (Domperidone) is a dopamine receptor (D2) antagonist.Don-A (Domperidone) is a selective peripheral dopamine antagonist at the D2 dopamine receptors in the Chemo-receptor Trigger Zone (CTZ) and stomach. Don-A (Domperidone) does not readily enter the central nervous system (the chemoreceptor trigger zone is considered to lie outside the blood brain barrier). Don-A (Domperidone) increases spontaneous gastric activity and antagonizes dopamine inhibition of gastric emptying. Don-A (Domperidone) has been shown to increase lower esophageal sphincter pressure and promotes esophageal and antral peristalsis and also increases pyloric dilation. Don-A (Domperidone) increases the frequency, amplitude, duration of duodenal contraction and reduces the small bowel transit time. Don-A (Domperidone) has no acetylcholine like effect.

Available in 60mL amber bottle; Box of 1’s.